Never fear Christians The likely hood that most of the unsaved that are causing us problems will make it through the first year of the tribulation is a very low.

Rev 9:14 Saying to the sixth angel which had the trumpet, Loose the four angels which are bound in the great river Euphrates.
Rev 9:15 And the four angels were loosed, which were prepared for an hour, and a day, and a month, and a year, for to slay the third part of men.

In raw numbers of the 6 billion people alive today 2 billion would be slain. Sounds nuclear to me.

Primary targets will probably be all major cities and control centers amongst men.